CTN Trial Progress

Randomizations for Active Studies as of the March 15 Trial Progress Report.

CTN-0080 - Enrolled 133

CTN-0098 - Enrolled 123

CTN-0099 - Enrolled 1428

CTN-0099-A-1 - Enrolled 96

CTN-0100
Discontinuation - Enrolled 128
Retention - Enrolled 727

CTN-0101 - Enrolled 196

CTN-0107 - Enrolled 123

CTN-0108 - Enrolled 77

Protocol Update: CTN-0139

CTN-0139, the Collaborative Care for Polysubstance use in Primary Care Settings (Co-Care) Trial, is studying a collaborative care intervention for polysubstance use involving opioids and/or stimulants, in adult primary care patients. Collaborative care is a team-based approach to managing chronic conditions that has been effective for depression and other behavioral health conditions, and has the potential to transform the delivery of substance use treatment in primary care settings.

This HEAL-funded CTN trial will test the Co-Care model versus enhanced usual care to reduce substance use and improve substance use-related functioning. The study will be conducted at 5 primary care sites (FQHCs and FQHC look-alikes). A pilot study will launch in February 2024 at one site, and the main study will start in August 2024 at all sites.

The Lead Team is currently conducting site selection activities and will be scheduling interviews in the coming weeks. If you have clinics who may be interested in participating, please contact Jasmine Fernando Jasmine.Fernando@nyulangone.org.

The Lead Investigator is Jennifer McNeely, MD, MS from the NY Node, and Co-Lead Investigator is Jane Liebschutz, MD, MPH from the Appalachian Node. For more information, contact the Project Director, Rebecca Stone Rebecca.Stone@nyulangone.org.

New from the ATTC Network

The Good, the Bad, and the Ugly of Good Samaritan Laws by Shane Reader, PhD. ATTC Messenger, March 2023.

ATTC's Pearls of Wisdom: Learning from Indigenous Ways of Knowing by Meg Schneider (National American Indian/Alaska Native ATTC) ATTC/NIATx Service Improvement Blog.

News from the New England Consortium Node

McLean/HMS Addictions Conference May 5-6, 2023: Keynote Address to be delivered by Kathleen Brady, MD, MPH, PI of the CTN Southern Consortium Node.

Gail D’Onofrio, MD, MS, received the "Recognizing Excellence Among Us: HEAL Director’s Awards for Excellence in Research."

Shelly Greenfield, MD, MPH, received the 2022 AAAP Founders’ Award for being an outstanding member of the community who works in the field of addiction and who has contributed significantly to the science, teaching, treatment or public policy in the addictions

David Fiellin, MD, received the 2023 James H. Tharp Award American Society of Addiction Medicine (ASAM) for contributions toward finding a solution to the problem of alcohol use disorder.

News from the Big South/West Node

Join the PIs of the CTN Big South/West Node at this year’s Texas Substance Use Symposium (TxSUS) for their workshop, Screening, Interventions, and Successful Collaborative Care Models for Primary Care.

TxSUS will be held at the Henry B. Gonzalez Convention Center in San Antonio, TX from March 27-28, 2023. The Big South/West workshop will be held on day 2 (March 28) from 9:30-11:30am (CST).

For more information and to register for the conference, visit the conference website.

NIH Request for Information (RFI)

Inviting input on use of a term like "preaddiction" for identifying and intervening in substance misuse and mild/early-stage substance use disorder

Recently, the term "preaddiction" has been proposed as a way to: raise public awareness about potentially harmful patterns of substance use, spur greater utilization of screening and brief intervention in clinical settings, prevent overdose, and promote the development of new interventions for potentially clinically significant substance misuse and/or early-stage SUD.

This RFI seeks input from people with lived experience of substance use, medical and scientific research communities, and other interested parties regarding the use of a term like preaddiction for identifying and intervening in potentially clinically significant substance misuse and/or early-stage SUD within healthcare settings.

Input is sought both on the terminology to describe this concept and the concept itself.

Find out more here.

Upcoming Events

2023 NIDA International Forum (free)
June 8-9, 2023 | Virtual
The Forum research symposium, poster session, and network-building activities focus on the range and quality of drug use and addiction research conducted around the world. Participants meet talented colleagues and learn about drug use and addiction research and policy issues in other countries, as well as the NIDA-supported fellowships and other programs that can support international collaborations.

2023 College on Problems of Drug Dependence (CPDD) Scientific Meeting
June 17-21, 2023
CPDD provides a national and international forum for scientists of diverse backgrounds to advance the understanding of molecular-neurobiological aspects of addictive disorders and, by the application of new scientific knowledge, to improve and develop treatments utilizing novel behavioral and pharmacological therapies.

Find more upcoming events at the NIDA website.