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Technology Transfer for the Implementation of a Clinical Trials Network on Drug Abuse and Mental Health Treatment in Mexico.

Revista Panamericana de Salud Pública (Pan American Journal on Public Health) 2015;38(3):233-242

Viviana E. Horigian, MD (University of Miami Miller School of Medicine, FNA Node), Rodrigo Marín-Navarrete, PhD (National Institute of Psychiatry, FNA Node), Rosa E. Verdeja (University of Miami Miller School of Medicine, FNA Node), Elizabeth Alonso, PhD (University of Miami Miller School of Medicine, FNA Node), María A. Perez (University of Miami Miller School of Medicine, FNA Node), José Fernández-Mondragón (National Institute of Psychiatry, FNA Node), Carlos Berlanga, MD (National Institute of Psychiatry, FNA Node), María Elena Medina-Mora, PhD (National Institute of Psychiatry, FNA Node), José Szapocznik, PhD (University of Miami Miller School of Medicine, FNA Node).

Low- and middle-income countries (LMIC) lack the research infrastructure and capacity to conduct rigorous substance abuse and mental health effectiveness clinical trials to guide clinical practice. A partnership between the Florida Node Alliance of the United States NIDA Clinical Trials Network and the National Institute of Psychiatry in Mexico was established in 2011 to improve substance abuse practice in Mexico. The purpose of this partnership was to develop a Mexican national clinical trials network of substance abuse researchers and providers capable of implementing effectiveness randomized clinical trials in community-based settings.

A technology transfer model was implemented and ran from 2011-2013. The Florida Node Alliance shared the "know how" for the development of the research infrastructure to implement randomized clinical trials in community programs through core and specific training modules, role-specific coaching, pairings, modeling, monitoring, and feedback. The technology transfer process was bi-directional in nature in that it was informed by feedback on feasibility and cultural appropriateness for the context in which practices were implemented. The Institute, in turn, led the effort to create the national network of researchers and practitioners in Mexico and the implementation of the first trial. A collaborative model of technology transfer was useful in creating a Mexican researcher-provider network that is capable of changing national practice in substance abuse research and treatment. Key considerations for transnational technology transfer are presented. (Article (Peer-Reviewed), PDF, English, 2015)

Keywords: Community health services | Dissemination | Health services research | Hispanics and Latinos | Mexican Clinical Trials Network on Addiction and Mental Health (REC-INPRFM) | Research design | Revista Panamericana de Salud Pública (journal)

Document No: 1175, PMID: 26758002.

Submitted by CTN Dissemination Librarians, 11/5/2015.


Alonso, Elizabeth mail
Berlanga, Carlos
Fernández-Mondragón, José mail
Horigian, Viviana E. mail
Marín-Navarrete, Rodrigo mail
Medina-Mora, María Elena
Perez, María A.
Szapocznik, José mail
Verdeja, Rosa E. mail
Florida Node Alliance www

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Supported by a grant from the National Institute on Drug Abuse to the University of Washington Alcohol and Drug Abuse Institute.
The materials on this site have neither been created nor reviewed by NIDA.
Updated 11/2015 --
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