Substance Use & Misuse 2017 (in press). [doi: 10.1080/10826084.2017.1298615]
Paul A. Nakonezny, PhD (University of Texas Southwestern Medical Center, TX Node), Wayne H. Denton, MD, PhD (Tallahassee Memorial Behavioral Health
Center), Arthur N. Westover, MD (University of Texas Southwestern Medical Center, TX Node), Bryon H. Adinoff, MD (University of Texas Southwestern Medical Center, TX Node).
It is reasonable to consider family discord after treatment as a potential target for a next-step intervention, since family discord is often comorbid with substance use disorders. This study evaluated family discord after completing an initial course of treatment as a predictor of substance use and retention in the community treatment program during follow-up. Patients were from two multisite randomized clinical trials implemented through the NIDA Clinical Trials Network (CTN-0004 and CTN-0005). There were 315 participants from Study 1 (12-week posttreatment follow-up) and 295 participants from Study 2 (8-week posttreatment follow-up). Negative binomial and logistic regression were used to estimate days of substance use and odds of retention in the community treatment program at follow-up, respectively, from family discord status.
Results found that participants experiencing family discord reported significantly more days of substance use during the posttreatment follow-up period than those who did not experience family discord in both Study 1 (9.12 vs. 2.89 days, p=.0001) and Study 2 (5.58 vs. 2.83 days, p=.0062). Family discord was significantly associated with lower retention in the community treatment program at follow-up in Study 1 (47.6% vs. 60.6%; p=.03), but not in Study 2 (55.3% vs. 64.9%; p=.11).
Conclusions: Family discord after an initial course of treatment might be a clinically relevant predictor of substance use. There is mixed support for a conclusion that family discord is associated with lower retention in the community treatment program at follow-up. Family discord warrants assessment after an initial course of treatment and may be a useful target for adaptive treatment intervention. (Article (Peer-Reviewed), PDF, English, 2017)
Keywords: Community health services | CTN platform/ancillary study | Family | Retention - Treatment | Substance Use & Misuse (journal)
Document No: 1269, PMID: 28557552.
Submitted by CTN Dissemination Librarians, 6/12/2017.