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Demographic and Clinical Characteristics of Treatment Seeking Women with Full and Subthreshold PTSD and Concurrent Cannabis and Cocaine Use Disorders.

Journal of Substance Abuse Treatment 2017;80:45-51. [doi: 10.1016/j.jsat.2017.06.007]

Lesia M. Ruglass, PhD (City College of New York), Alina Shevorykin, MA (Pace University), Christina Brezing, MD (Columbia University, GNY Node), Mei-Chen Hu, PhD (Columbia University, GNY Node), Denise A. Hien, PhD (Columbia University, GNY Node)

While the detrimental effects of concurrent substance use disorders (SUDs) are now being well documented, very few studies have examined this comorbidity among women with posttraumatic stress disorder (PTSD). Data for these analyses were derived from the "Women and Trauma" study (CTN-0015) conducted within the NIDA Clinical Trials Network. Women with full or subthreshold PTSD and co-occurring cannabis use disorder (CUD) and cocaine use disorder (COD; N=99) were compared to their counterparts with co-occurring CUD only (N=26) and co-occurring COD only (N=161) on rates of trauma exposure, psychiatric disorders, psychosocial problems, and other substance use utilizing a set of multivariate logistic regressions. In models adjusted for age and race/ethnicity, women with PTSD and COD only were significantly older than their counterparts with CUD only and concurrent CUD+COD. Relative to those with CUD only, women with concurrent CUD+COD had higher odds of adult sexual asault. Relative to those with COD only, women with concurrent CUD+COD had higher odds of alcohol use disorder in the past 12 months. Finally, relative to those with CUD only, women with COD only had higher odds of ever being arrested/convicted and adult sexual assault.

Conclusions: The higher rates of adult sexual assault and alcohol use disorder among those with concurrent CUD+COD suggest the need for trauma-informed approaches that can response to the needs of this dually-diagnosed population. Moreover, the causal link between repeated traumatic stress exposure and polysubstance use requires further examination. (Article (Peer-Reviewed), PDF, English, 2017)

Keywords: Alcohol | Cocaine | Co-occurring disorders | CTN platform/ancillary study | Marijuana | Post-traumatic stress disorder (PTSD) | Trauma | Women | Journal of Substance Abuse Treatment (journal)

Document No: 1275.

Submitted by the CTN Dissemination Librarians (7/7/2017).

Brezing, Christina
Hien, Denise A. mail
Hu, Mei-Chen
Ruglass, Lesia M. mail
Shevorykin, Alina
NIDA-CTN-0015 www

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Supported by a grant from the National Institute on Drug Abuse to the University of Washington Alcohol and Drug Abuse Institute.
The materials on this site have neither been created nor reviewed by NIDA.
Updated 7/2017 --
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