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Patterns of Substance Use and Arrest Histories Among Hospitalized HIV Drug Users: A Latent Class Analysis.

AIDS and Behavior 2018;22(9):2757-2765. [doi: 10.1007/s10461-017-2024-y]

Karen Shiu-Yee, MPH (Columbia University), Ahnalee M. Brincks, PhD (Michigan State University), Daniel J. Feaster, PhD (University of Miami), Jemima A. Frimpong, PhD (Johns Hopkins), Ank Nijhawan, MD (UT Southwestern Medical Center), Raul N. Mandler, MD (National Institute on Drug Abuse), Robert P. Schwartz, MD (Friends Research Institute), Carlos del Rio, MD (Rollins School of Public Health), Lisa R. Metsch, PhD (Columbia University).

People living with HIV (PLWH) who use substances continue to have shorter life expectancies and worse health outcomes than PLWH who do not use substances. Another important contributor to factors that can affect the health of PLWH who use substances is these individuals' frequent interactions with the criminal justice system.

This analysis of baseline data from the NIDA Clinical Trials Network CTN-0049 study (Project HOPE) aimed to expand the current literature examining the complex relationships between PLWH who use substances' substance use behaviors and criminal justice involvement to better inform future studies and program implementation.

Researchers performed latent class analyses (LCA) to identify discrete classes, or clusters, of PLWH based on their past year substance use behaviors and lifetime arrest history. Multinomial logistic regressions were also performed to identify key characteristics associated with class membership. Five classes of substance users were identified (minimal drug users, cocaine users, substantial cocaine/hazardous alcohol users, problem polysubstance users, substantial cocaine/heroin users) as well as 3 classes of arrest history (minimal arrests, non-drug arrests, drug-related arrests).

While several demographic variables such as age and being Black or Hispanic were associated with class membership for some of the latent classes, participation in substance use treatment was the only covariate that was significantly associated with membership in all classes in both substance use and arrest history LCA models.

Conclusions: This analysis supports the utility of latent class analysis in revealing complex patterns of behaviors. The findings are a first step toward better understanding the complex dynamics of substance use and of criminal justice system involvement among PLWH that may be useful in informing the future direction of research studies aiming to examine the complex interactions among substance use, criminal justice involvement, and HIV care. HIV intervention strategies may need to take into consideration such nuanced differences to better inform patient care. (Article (Peer-Reviewed), PDF, English, 2018)

Keywords: Criminal justice system | CTN platform/ancillary study | HIV/AIDS | Minority groups | AIDS and Behavior (journal)

Document No: 1297, PMID: 29305761, PMCID: PMC6033678 (available 9/1/2019).

Submitted by CTN Dissemination Librarians, 1/11/2018.


Brincks, Ahnalee M.
del Rio, Carlos mail
Feaster, Daniel J. mail
Frimpong, Jemima A.
Mandler, Raul N. mail
Metsch, Lisa R. search mail
Nijhawan, Ank
Schwartz, Robert P. search mail
Shin-Yee, Karen search
NIDA-CTN-0049 www
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Supported by a grant from the National Institute on Drug Abuse to the University of Washington Alcohol and Drug Abuse Institute.
The materials on this site have neither been created nor reviewed by NIDA.
Updated 8/2018 --
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