Poster presented at the College on Problems of Drug Dependence (CPDD) annual meeting, Quebec City, Canada, June 16-21, 2007.
Malcolm S. Reid, Ph.D. (New York University School of Medicine, NY Node), Bryan Fallon, PhD (Mount Sinai Hospital, NY Node), Susan C. Sonne, PharmD (Medical University of South Carolina, SC Node), Robert Hiott, MEd (Behavioral Health Services of Pickens County, SC Node), Frank Flammino, PhD, MBA (New York University School of Medicine), Edward V. Nuñes, MD (Columbia University and New York State Psychiatric Institute, LI Node), Eva Kourniotis, MS (New York State Psychiatric Institute, LI Node), Ronald Brady, MD (Narco Freedom, Inc., LI Node), Paul Rinaldi, PhD (St. Luke's Roosevelt Hospital Center, LI Node), Huiping Jiang, PhD (New York State Psychiatric Institute, LI Node), Cynthia L. Arfken, PhD (Wayne State University, GL Node), Eric Pihlgren, PhD (Wayne State University, GL Node), Louis Giordano, PhD (Duke University, NC Node), James A. Robinson, MEd (Nathan Kline Institute for Psychiatric Reserach, NY/LI Node), John Rotrosen, MD (New York University, NY Node).
A smoking cessation study was performed at community-based outpatient substance abuse rehabilitation programs in the National Drug Abuse Treatment, Clinical Trials Network (CTN). Drug or alcohol dependent patients, who smoked more than 10 cigarettes/day and had been enrolled in substance abuse treatment for at least 1 month, were randomly selected on a 2:1 ratio to receive smoking cessation treatment as an adjunct to substance abuse treatment as usual (SC), or substance abuse treatment as usual (TAU) without the smoking cessation component. Participants assigned to SC treatment were provided one week of group counseling prior to the Target Quit Date and 8 weeks of group counseling plus transdermal nicotine patch following the Target Quit Date. Smoking abstinence rates in the SC group reached 10% during treatment, and remained above 5% at the 13 and 26 week follow-up visits. Smoking behavior in the SC group underwent a 75% reduction in cigarettes smoked/day, a decrease in exhaled CO levels, and a drop in cigarette craving and nicotine withdrawal ratings during treatment. Smoking behavior in the TAU group remained unchanged during treatment and abstinence rates were negligible. Compliance with smoking cessation treatment was moderate, and both counseling attendance and nicotine patch treatment adherence were positively associated with smoking abstinence rates. Association of substance abuse variables with smoking abstinence rates will be discussed. These findings demonstrate that smoking cessation treatment, when given concurrently with outpatient substance abuse treatment, results in significant reductions in daily smoking and modest levels of smoking abstinence. (Poster, PowerPoint slides, English, 2007)
Keywords: Nicotine replacement therapy | Pharmacological therapy | Smoking | College on Problems of Drug Dependence (CPDD) annual meeting, 2007
Document No: 208
Submitted by Malcolm Reid, PhD, NY Node, 7/2007.