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Issues in Designing and Implementing a Spanish-Language Multi-Site Clinical Trial.

American Journal on Addictions 2007;16(3):206-215. [doi: 10.1080/10550490701375707]

Lourdes Suarez-Morales, PhD (University of Miami School of Medicine, FL Node), Julie Matthews (Advanced Behavioral Health, Inc., NE Node), Steve Martino, PhD (Connecticut VA Healthcare Center, NE Node), Samual A. Ball, PhD (Yale University School of Medicine, NE Node), Carmen L. Rosa, MS (Center for the Clinical Trials Network, NIDA), Christiane Farentinos, MD, CADC II (ChangePoint, Inc., OR/HI Node), José Szapocznik, PhD (University of Miami School of Medicine, FL Node), Kathleen M. Carroll, PhD (Yale University School of Medicine, NE Node).

To address at least in part health disparities in Hispanic populations, the NIDA Clinical Trials Network implemented the first multi-site randomized clinical trial of substance abuse treatment conducted entirely in Spanish, protocol CTN-0021, "Motivational Enhancement Treatment to Improve Treatment Engagement and Outcome for Spanish-Speaking Individuals Seeking Treatment for Substance Abuse." This trial was intended to evaluate the effectiveness of Motivational Enhancement Therapy in a diverse population of Hispanics. In the conduct of this trial, several barriers to the successful implementation of a Spanish-language multi-site trial had to be addressed, including the appropriate translation of assessment instruments, shortage of appropriately trained Spanish-speaking clinical staff, and barriers to recruitment and retention of this population. To encourage similar research, strategies are described in this article that were developed by the study team to meet these challenges. (Article (Peer-Reviewed), PDF, English, 2007)

Keywords: Behavior therapy | Clinical trials - Methods | Community health services | CTP training | Hispanics and Latinos | Minority groups | Motivational Enhancement Therapy (MET) | Research design | Retention - Research | Screening and assessment instruments | American Journal on Addictions (journal)

Document No: 215, PMID: 17612825, PMCID: PMC3628724.

Submitted by CTN Dissemination Librarians, 6/25/2007.

AUTHORS SEARCH LINK
Ball, Samuel A. search mail
Carroll, Kathleen M. search mail
Farentinos, Christiane search mail
Martino, Steve search mail
Matthews, Julie search mail
Rosa, Carmen L. search mail
Suarez-Morales, Lourdes search mail
Szapocznik, Jose search mail
PROTOCOLS
NIDA-CTN-0021 search www
PARTICIPATING NODES
Florida Node Alliance (Lead) search www
New England Consortium (formerly New England) (Lead) search www
Greater New York (formerly Long Island) search www
Rocky Mountain Regional search www
Southwest search www
Western States (formerly Oregon/Hawaii) search www

Supported by a grant from the National Institute on Drug Abuse to the University of Washington Alcohol and Drug Abuse Institute.
The materials on this site have neither been created nor reviewed by NIDA.
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