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Adverse Events in an Integrated Trauma-Focused Intervention for Women in Community Substance Abuse Treatment.

Journal of Substance Abuse Treatment 2008;35(3):304-311. [doi: 10.1016/j.jsat.2007.12.001].

Therese Killeen, PhD, APRN (Medical University of South Carolina, SC Node), Denise A. Hien, PhD (Columbia University School of Social Work, LI Node), Aimee Campbell, MSW (Columbia University School of Social Work, LI Node), Chanda Brown, PhD, MSW (Charleston Center, SC Node), Cheri Hansen, PhD (The Village South, Inc., FL Node), Huiping Jiang, PhD (New York State Psychiatric Institute, LI Node), Allison Kristman-Valente, MSW (Residence XII, PN Node), Christine Neuenfeldt, PhD (Gateway Community Services, FL Node), Nicci Rocz-de la Luz, MS (The Village South, Inc., FL Node), Royce Sampson, MSN, APRN (Medical University of South Carolina, SC Node), Lourdes Suarez-Morales, PhD (University of Miami Miller School of Medicine, FL Node), Elizabeth A. Wells, PhD (University of Washington School of Social Work, PN Node), Gregory S. Brigham, PhD (Maryhaven, Inc., OV Node), Edward V. Nunes, MD (Columbia University and New York State Psychiatric Institute, LI Node).

A substantial number of women who enter substance abuse treatment have a history of trauma and meet criteria for posttraumatic stress disorder (PTSD). Fear regarding the extent to which PTSD treatment can evoke negative consequences remains a research question. This study, part of CTN-0015 ("Women's Treatment for Trauma and Substance Use Disorders"), explored adverse events related to the implementation of an integrated treatment for women with trauma and substance use disorder (Seeking Safety) compared with a nontrauma-focused intervention (Women's Health Education). Three hundred fifty-three women enrolled in community substance abuse treatment were randomized to 1 of the 2 study groups and monitored weekly for adverse events. There were no differences between the two intervention groups in the number of women reporting study-related adverse events (28 [9.6%] for the Seeking Safety group and 21 [7.2%] for the Women's Health Education group). Implementing PTSD treatment in substance abuse treatment programs appears to be safe, with minimal impact on intervention-related adverse psychiatric and substance abuse symptoms. More research is needed on the efficacy of such interventions to improve outcomes of PTSD and substance use. (Article (Peer-Reviewed), PDF, English, 2008)

Keywords: Gender-specific interventions | Post-traumatic stress disorder | Seeking Safety program | Trauma | Women | Women's Health Education program | Journal of Substance Abuse Treatment (journal)

Document No: 262, PMID: 18294804

Submitted by CTN Dissemination Librarians (3/8/2008).

Brigham, Gregory S. search mail
Brown, Chanda search mail
Campbell, Aimee search mail
Hansen, Cheri search mail
Hien, Denise search mail
Jiang, Huiping search mail
Killeen, Therese search mail
Kristman-Valente, Allison search mail
Neuenfeldt, Christine search mail
Nunes, Edward V. search mail
Rocz-de la Luz, Nicci search
Sampson, Royce search mail
Suarez-Morales, Lourdes search mail
Wells, Elizabeth A. search mail
NIDA-CTN-0015 search www
Greater New York (formerly Long Island and New York) (Lead) search www
Florida Node Alliance search www
Ohio Valley search www
Pacific Northwest search www
Southern Consortium search www

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