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CTN-0019
Primary
Outcomes

Effectiveness of HIV/STD Sexual Risk Reduction Groups for Women in Substance Abuse Treatment Programs: Results of a NIDA Clinical Trials Network Trial.

Journal of Acquired Immune Deficiency Syndromes 2008;48(5):581-589. [doi: 10.1097/QAI.0b013e31817efb6e]

Susan Tross, PhD (New York State Psychiatric Institute, LI Node), Aimee N. C. Campbell, MSW (Columbia University School of Social Work, LI Node), Lisa R. Cohen, PhD (Columbia University School of Social Work, LI Node), Donald A. Calsyn, PhD (Alcohol & Drug Abuse Institute, University of Washington, PN Node), Martina Pavlicova, PhD (University of Pennsylvania, DV Node), Gloria M. Miele, PhD (New York State Psychiatric Institute, LI Node), Mei-Chen Hu, PhD (Columbia University Mailman School of Public Health, NY Node), Louise F. Haynes, MSW (Lexington/Richland Alcohol and Drug Abuse Council, SC Node), Nancy Nugent, MS (Beth Israel Medical Center, NY Node), Weijin Gan, MD, PhD (New York University Child Study Center, New York University School of Medicine, NY Node), Mary A. Hatch-Maillette, PhD (Alcohol & Drug Abuse Institute, University of Washington, PN Node), Raul N. Mandler, MD (National Institute on Drug Abuse, NIDA CCTN), Paul McLaughlin, MA (Hartford Dispensary, NE Node), Nabila El-Bassel, DSW (Columbia University School of Social Work, LI Node), Paul Crits-Christoph, PhD (Treatment Research Center, University of Pennsylvania School of Medicine, DV Node), Edward V. Nunes, MD (Columbia University and New York State Psychiatric Institute, LI Node).

This is the Primary Outcomes Article for CTN-0019. Since drug-involved women are among the fastest growing groups with AIDS, sexual risk reduction intervention for them is a public health imperative. The objective of this study, part of protocol CTN-0019 ("Reducing HIV/STD Risk Behaviors: A Research Study for Women in Drug Abuse Treatment"), was to test the effectiveness of HIV/STD safer sex skills building (SSB) groups for women in community drug treatment. The study used a randomized trial of SSB versus standard HIV/STD Education (HE), with assessments at baseline, 3, and 6 months. Women were recruited from 12 methadone or psychosocial treatment programs in the National Drug Abuse Treatment Clinical Trials Network. Five hundred and fifteen women who had had at least one unprotected vaginal or anal sex occasion (USO) with a male partner in the past six months were randomized. In SSB, five 90-minute groups used problem solving and skills rehearsal to increase HIV/STD risk awareness, condom use, and partner negotiation skills. In HE, one 60-minute group covered HIV/STD disease, testing, treatment, and prevention information.

The main outcome measured was the number of USOs at follow-up. A significant difference in mean USOs was obtained between SSB and HE over time (F = 67.2, P < 0.0001). At 3 months, significant decrements were observed in both conditions. At 6 months, SSB maintained the decrease and HE returned to baseline (P < 0.0377). Women in SSB had 29% fewer USOs than those in HE.

Conclusions: Skills building interventions can produce ongoing sexual risk reduction in women in community drug treatment. (Article (Peer-Reviewed), PDF, English, 2008)

Keywords: Community health services | Condom use | CTN primary outcomes | Gender-specific interventions | HIV/AIDS | Safer Sex Skills Building (SSSB) | Sexual risk behavior | Sexually transmitted diseases | Skills building | Women | Journal of Acquired Immune Deficiency Syndromes (journal)

Document No: 293, PMID: 18645513, PMCID: PMC2723122

Submitted by CTN Dissemination Librarians, 8/25/2008.

AUTHORS SEARCH LINK
Calsyn, Donald A. search mail
Campbell, Aimee N. C. search mail
Cohen, Lisa R. search mail
Crits-Christoph, Paul search mail
El-Bassel, Nabila search
Gan, Weijin search
Hatch-Maillette, Mary A. search mail
Haynes, Louise F. search mail
Hu, Mei-Chen search
Mandler, Raul N. search mail
McLaughlin, Paul search mail
Miele, Gloria M. search mail
Nugent, Nancy search
Nunes, Edward V. search mail
Pavlicova, Martina search
Tross, Susan search mail
PROTOCOLS
NIDA-CTN-0019 search www
PARTICIPATING NODES
Greater New York (formerly Long Island) (Lead) search www
Delaware Valley search www
New England Consortium (formerly New England) search www
North Carolina search www
Ohio Valley search www
Pacific Region search www
Southern Consortium search www
Pacific Northwest search www

Supported by a grant from the National Institute on Drug Abuse to the University of Washington Alcohol and Drug Abuse Institute.
The materials on this site have neither been created nor reviewed by NIDA.
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