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HIV Sex Risk Behaviors and PTSD: Secondary Findings from a NIDA Clinical Trials Network Randomized Controlled Trial of Women in Community-Based Substance Abuse Treatment.

Poster presented at the College on Problems of Drug Dependence (CPDD) annual meeting, San Juan, Puerto Rico, June 14-19, 2008.

Denise A. Hien, PhD (Columbia University, LI Node), Therese Killeen, PhD, APRN (Medical University of South Carolina, SC Node), Aimee Campbell, MSW (Columbia University, LI Node), Huiping Jiang, PhD (Columbia University, LI Node), Edward V. Nuñes, MD (Columbia University, LI Node).

Heterosexual women with substance use disorders (SUD) are at high risk for HIV. A substantial number of women in substance abuse treatment have histories of interpersonal violence, as well as comorbid psychological disorders, such as posttraumatic stress disorder (PTSD). The aim of this study was to examine HIV sexual risk behaviors of treatment-seeking women with SUD and PTSD and the treatment effect of two interventions on sexual risk outcomes. Secondary analyses were conducted with 353 women meeting criteria for SUD and full or subthreshold PTSD enrolled in a study of the effectiveness of two group interventions (CTN-0015, "Women's Treatment for Trauma and Substance Use Disorders"): 1) an integrated treatment for SUD and PTSD called "Seeking Safety," and 2) a health education attention control called "Women's Health Education program." Bivariate associations between baseline demographic, diagnostic characteristics and HIV sex risk behavior were examined. Zero-inflated negative binomial model regressions were run to assess differences in sexual risk behaviors between intervention groups. At baseline, 54% of women were sexually active in the previous 30 days, averaging one sexual partner and 5.4 unprotected sexual occasions. Women with more substance use reported more sexual partners and unprotected sex. The integrated treatment for PTSD and SUD had a significant impact in decreasing sexual risk behaviors post-treatment (p=.05, 95% CI 0.51-1.03). In conclusion, women in outpatient substance abuse treatment with comorbid PTSD may reduce unprotected sexual encounters by participating in trauma integrated treatment. Increasing PTSD coping skills and understanding the role of trauma may enhance feelings of empowerment or increase efficacy to make choices that will improve sexual health. (Poster, PowerPoint slides, English, 2008)

Keywords: CTN platform/ancillary study | Gender-specific interventions | Post-traumatic stress disorder | Seeking Safety program | Trauma | Women | Women's Health Education program | College on Problems of Drug Dependence (CPDD) annual meeting, 2008

Document No: 317

Submitted by Denise Hien, PhD, Lead Investigator for CTN-0015 (9/16/2008).

Campbell, Aimee search mail
Hien, Denise search mail
Jiang, Huiping search mail
Killeen, Therese search mail
Nunes, Edward V. search mail
NIDA-CTN-0015 search www
Greater New York (formerly Long Island and New York) (Lead) search www
Florida Node Alliance search www
Ohio Valley search www
Pacific Northwest search www
Southern Consortium search www

Supported by a grant from the National Institute on Drug Abuse to the University of Washington Alcohol and Drug Abuse Institute.
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