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Gender Differences at Presentation for Treatment-Seeking Opiate Dependence.

Poster presented at the College on Problems of Drug Dependence (CPDD) annual meeting, Reno/Sparks, Nevada, June 20-25, 2009.

Louise F. Haynes, MSW (Medical University of South Carolina, SC Node), Rickey E. Carter, PhD (Medical University of South Carolina, SC Node), Sudie E. Back (Medical University of South Carolina, SC Node), Rebecca Payne (Medical University of South Carolina, SC Node), Maureen Hillhouse, PhD (Integrated Substance Abuse Programs, UCLA, PA Node).

Significant gender differences in substance use disorders have been reported in the literature. Little is known, however, with regard to gender differences in patients presenting with opiate dependence. The NIDA-sponsored Clinical Trials Network study of buprenorphine taper schedules (CTN-0003) was designed to compare the effects of a short and long taper schedule of buprenorphine on participant outcomes. The study was conducted form 2003-2005 at 11 participating treatment programs in 10 cities across the country. This poster reports on a study that aimed to examine differences at presentation between males and females seeking outpatient treatment for opiate dependence screened for inclusion in CTN-0003. Inclusion criteria used in the analysis were DSM-IV diagnosis of opioid dependence and a non-missing gender reported. Gender-specific profiles were observed with regard to substance use severity, craving, and impairment in associated areas of functioning. Overall, women demonstrated a more severe clinical profile than men, as evidenced by significantly higher ASI-Lite subscale scores assessing drug use, occupational functioning, family and social relationship functioning, medical and psychiatric problems. As compared to men, women also had more past and active medical conditions and reporter higher craving for opiates. These findings highlight the potential usefulness of gender-sensitive assessment and treatment interventions. (Poster, Power-Point slides, English, 2009)

Keywords: Addiction Severity Index-Lite (ASI-Lite) | Buprenorphine/Naloxone | Community health services | CTN platform/ancillary study | Gender differences | Gender-specific interventions | Opioid dependence | Pharmacological therapy | Suboxone | Taper schedules | Women | College on Problems of Drug Dependence (CPDD) annual meeting, 2009

Document No: 415

Submitted by Louise F. Haynes, MSW, 2/11/2010.

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