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NIDA's Clinical Trials Network Can Facilitate Comparative Effectiveness Research on Drug Addiction Treatments.

Poster presented at the College on Problems of Drug Dependence (CPDD) annual meeting, Scottsdale, AZ, June 12-17, 2010.

Udi Ghitza, PhD, Steven Sparenborg, PhD, David S. Liu, MD, Betty Tai, PhD (all from the Center for the Clinical Trials Network (CCTN))

Recent Congressionally-mandated reports on Comparative Effectiveness Research (CER) define CER as "the generation and synthesis of evidence that compares the benefits and harms of alternative methods to prevent, diagnose, treat, and monitor a clinical condition or to improve the delivery of care," in order to "assist patients, clinicians, purchasers, policy makers, and the public to make informed decisions that will improve health care at both the individual and population levels." The purposes of CER are congruent with the mission of the National Drug Abuse Treatment Clinical Trials Network (CTN): to ensure the transfer of promising research results to physicians, clinicians, providers, and patients by conducting studies of behavioral, pharmacological, and integrated treatments in rigorous, multi-site clinical trials to determine effectiveness across a broad range of community-based treatment settings and diversified patient populations. The CTN's research infrastructure includes clinical expertise centered in major universities and local community-based addiction treatment programs studying patient care in real-world settings. Ways in which the CTN can enhance its ability to conduct addiction CER are discussed, including a description of possible future CER studies in the network: a smoking cessation pharmacotherapy options study that would compare nicotine replacement therapy, bupropion, and varenicline; and a co-morbidity of opiates and alcohol abuse study. (Poster, PDF, English, 2010)

Keywords: Comparative effectiveness research | CTN research agenda | Dissemination | Evidence-based treatment | College on Problems of Drug Dependence (CPDD) annual meeting, 2010

Document No: 496

Submitted by Udi Ghitza, PhD, Center for the Clinical Trials Network (CCTN), 6/28/2010.

Ghitza, Udi search mail
Liu, David S. search mail
Sparenborg, Steven search mail
Tai, Betty search mail

Supported by a grant from the National Institute on Drug Abuse to the University of Washington Alcohol and Drug Abuse Institute.
The materials on this site have neither been created nor reviewed by NIDA.
Updated 6/2010 --