Use your browser's back button to choose another title or click here for a New Search.



How to Get the Poster

 Open poster (pdf)

 

Bookmark and Share

Predictors of Study Retention in Drug Abuse Treatment Trials.

Poster presented at the College on Problems of Drug Dependence (CPDD) annual meeting, Scottsdale, AZ, June 12-17, 2010.

Jeffrey E. Korte, PhD, Kathryn M. Magruder, PhD, MPH, Susan C. Sonne, PharmD, Royce Sampson, MSN, APRN-BC, Kathleen T. Brady, MD, PhD (all from Medical University of South Carolina, SC Node).

Participant retention is critically important for clinical research studies in the area of addictions. This study, using data from fifteen trials in the National Drug Abuse Treatment Clinical Trials Network, sought to examine predictors of retention in a series of treatment outcome studies. Studies were combined, defining retention through the final follow-up visit, and multivariate logistic regression models were used to assess predictors of study retention, focusing on age, gender, and ethnicity (non-Hispanic White, African American, and Hispanic/Other). Results found no clear pattern, however retention seemed higher in adult pharmacological trials and lower in sexual risk reduction trials. Younger participants were more likely to drop out and, in comparison to African American participants, non-Hispanic Whites were more likely and Hispanic/Others less likely, to drop out. In terms of gender, no significant difference was found between the sexes, though a significant interaction was discovered between ethnicity and gender in relation to study retention. This interaction was largely driven by Hispanic/Other women (not in methadone treatment), who were approximately 40% less likely to be lost to follow-up than their African American counterparts. The results suggest that strategies focused on improving study retention in younger subjects, and in non-Hispanic females, may be particularly important for increasing participant retention and improving the validity of clinical trial data. (Poster, PowerPoint slides, English, 2010)

Keywords: Adolescents | African Americans | CTN platform/ancillary study | Gender differences | Hispanics and Latinos | Minority groups | Retention - Research | College on Problems of Drug Dependence (CPDD) annual meeting, 2010

Document No: 506

Submitted by Jeffrey Korte, PhD, Medical University of South Carolina, SC Node, 7/8/2010.

AUTHORS SEARCH LINK
Brady, Kathleen T. search mail
Korte, Jeffrey E. search mail
Magruder, Kathryn M. search mail
Sampson, Royce search mail
Sonne, Susan C. search mail
PROTOCOLS
NIDA-CTN-0001 search www
NIDA-CTN-0002 search www
NIDA-CTN-0003 search www
NIDA-CTN-0004 search www
NIDA-CTN-0005 search www
NIDA-CTN-0006 search www
NIDA-CTN-0007 search www
NIDA-CTN-0009 search www
NIDA-CTN-0010 search www
NIDA-CTN-0011 search www
NIDA-CTN-0013 search www
NIDA-CTN-0015 search www
NIDA-CTN-0018 search www
NIDA-CTN-0019 search www
NIDA-CTN-0021 search www

Supported by a grant from the National Institute on Drug Abuse to the University of Washington Alcohol and Drug Abuse Institute.
The materials on this site have neither been created nor reviewed by NIDA.
Updated 7/2010 -- http://ctndisseminationlibrary.org/display/506.htm
info@ctndisseminationlibrary.org