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Helping Alliance, Retention, and Treatment Outcomes: A Secondary Analysis from the NIDA Clinical Trials Network Women and Trauma Study.

Substance Use & Misuse 2012;47(6):695-707. [doi: 10.3109/10826084.2012.659789]

Lesia M. Ruglass, PhD (City College of New York, GNY Node), Gloria M. Miele, PhD (New York State Psychiatric Institute, GNY Node), Denise A. Hien, PhD (Columbia University College of Physicians and Surgeons, GNY Node), Aimee N. C. Campbell, MSW, PhD (New York State Psychiatric Institute, GNY Node), Mei-Chen Hu, PhD (Columbia University, GNY Node), Nathilee Caldeira, PhD (New York University, GNY Node), Huiping Jiang, PhD (New York State Psychiatric Institute, GNY Node), Lisa C. Litt, PhD (Columbia University, GNY Node), Therese Killeen, PhD, ARPN (Medical University of South Carolina, SC Node), Mary A. Hatch-Maillette, PhD (Alcohol & Drug Abuse Institute, UW, PN Node), Lisa M. Najavits, PhD (Boston University, Harvard Medical Center), Chanda Brown, PhD (Charleston Center, SC Node), James A. Robinson, MEd (Nathan Kline Institute for Psychiatric Research, GNY Node), Gregory S. Brigham, PhD (Maryhaven, Inc., OV Node), Edward V. Nunes, MD (Columbia University College of Physicians and Surgeons, GNY Node).

In this secondary analysis of data from the National Drug Abuse Treatment Clinical Trials Network protocol CTN-0015 ("Women's Treatment for Trauma and Substance Use Disorders"), researchers examined the association between the therapeutic alliance and treatment outcomes among 223 women with posttraumatic stress disorder (PTSD) and substance use disorders. General linear models indicated that women who received Seeking Safety, a cognitive-behavioral treatment, had significantly higher alliance ratings than those in Women's Health Education, a control group.

Conclusions: Alliance was related to significant decreases in PTSD symptoms and higher attendance in both interventions. Alliance was not related to substance use outcomes. In all, this study demonstrates that this typically challenging group of women can develop a strong therapeutic alliance within a relatively brief treatment episode in a group format, facilitating reductions in PTSD symptoms and leading to treatment retention. (Article (Peer-Reviewed), PDF, English, 2012)

Keywords: CTN platform/ancillary study | Co-occurring disorders | Gender-specific interventions | Post-traumatic stress disorder (PTSD) | Retention - Treatment | Seeking Safety program | Therapeutic alliance | Trauma | Women | Women's Health Education program | Substance Use & Misuse (journal)

Document No: 803, PMID: 22475068, PMCID: PMC3639137.

Submitted by CTN Dissemination Librarians, 4/5/2012

Brigham, Gregory S. search mail
Brown, Chanda search mail
Caldeira, Nathilee search  
Campbell, Aimee N. C. search mail
Jiang, Huiping search
Killeen, Therese search mail
Hatch-Maillette, Mary A. search mail
Hien, Denise search mail
Hu, Mei-Chen search
Litt, Lisa C. search mail
Miele, Gloria M. search mail
Najavits, Lisa M. search
Nunes, Edward V. search mail
Robinson, James A. search mail
Ruglass, Lesia M. search
NIDA-CTN-0015 search www
Greater New York (Lead) search www
Florida Node Alliance search www
Ohio Valley search www
Pacific Northwest search www
Southern Consortium search www

Supported by a grant from the National Institute on Drug Abuse to the University of Washington Alcohol and Drug Abuse Institute.
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