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Impulsivity is Associated with Treatment Non-Completion in Cocaine- and Methamphetamine-Dependent Patients but Differs in Nature as a Function of Stimulant-Dependence Diagnosis.

Journal of Substance Abuse Treatment 2013;44(5):541-547. [doi: 10.1016/j.jsat.2012.12.005]

Theresa M. Winhusen, PhD (University of Cincinnati/CinARC, OV Node), Daniel F. Lewis (University of Cincinnati/CinARC, OV Node), Bryon H. Adinoff, MD (University of Texas Southwestern Medical Center, TX Node), Gregory S. Brigham, PhD (Maryhaven, Inc., OV Node), Frankie B. Kropp, MS (University of Cincinnati/CinARC, OV Node), Dennis M. Donovan, PhD (Alcohol & Drug Abuse Institute, University of Washington, PN Node), Cindy L. Seamans, PhD (Nexus Recovery Center, Inc., TX Node), Candace C. Hodgkins, PhD, LMHC (Gateway Community Services, Inc., FNA Node), Jessica C. DiCenzo, MSW (Recovery Centers of King County, PN Node), Christopher L. Botero (ChangePoint, Inc., WS Node), Davina R. Jones (Willamette Family, Inc., WS Node), Eugene C. Somoza, MD, PhD (University of Cincinnati/CinARC, OV Node).

This is the Primary Outcomes Article for CTN-0031-A-1. Greater impulsivity, assessed by the Barratt Impulsiveness Scale-11 (BIS-11) and Stroop interference scores, has been associated with treatment completion in cocaine-dependent patients. This study, an ancillary investigation of data from the National Drug Abuse Treatment Clinical Trials Network study CTN-0031, evaluated the relationships among impulsivity, stimulant-dependence diagnosis, and treatment completion. Six sites evaluating 12-step facilitation for stimulant abusers obtained BIS-11 and Stroop Color Word test results from 182 methamphetamine- and/or cocaine-dependent participants. Methamphetamine-dependent, relative to cocaine-dependent, participants evidenced significantly greater BIS-11 non-planning and total scores. There was a trend for poorer response inhibition, measured by the Stroop, in cocaine-dependent, relative to methamphetamine-dependent, participants. Accounting for other factors related to treatment completion, BIS-11 motor score, and assessing the tendency to act without thinking predicted treatment completion for both cocaine-dependent and methamphetamine-dependent patients.

Conclusions: These results suggest that methamphetamine-dependent and cocaine-dependent patients may have different impulsivity profiles but that the BIS-11 may be useful in identifying both methamphetamine-dependent and cocaine-dependent patients who are at risk for treatment non-completion. (Article (Peer-Reviewed), PDF, English, 2013)

Keywords: Barratt Impulsiveness Scale-11 (BIS-11) | Behavior therapy | Cocaine | CTN platform/ancillary study | Impulsivity | Methamphetamine | Retention - Treatment | Screening and assessment instruments | Stimulant abuse | Stroop Color Word Test | Twelve-step programs | Journal of Substance Abuse Treatment (journal)

Document No: 932, PMID: 23305820, PMCID: PMC3602401.

Submitted by CTN Dissemination Librarians, 1/14/2013.

Adinoff, Bryon H. search mail
Botero, Christopher L. search
Brigham, Gregory S. search mail
DiCenzo, Jessica C. search
Donovan, Dennis M. search mail
Hodgkins, Candace C. search mail
Jones, Davina R. search mail
Kropp, Frankie B. search mail
Lewis, Daniel F. search mail
Seamans, Cindy L. search mail
Somoza, Eugene C. search mail
Winhusen, Theresa M. search mail
NIDA-CTN-0031-A-1 search www
Pacific Northwest (Lead) search www
Appalachian Tri-State search www
Florida Node Alliance search www
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