National Drug Abuse Treatment 

  PROTOCOL NIDA-CTN-0010-A-2


Comorbid Conditions in Adolescents with Opioid Versus Alcohol/Marijuana Use Disorders

Geetha Subramaniam, M.D.
Lead Investigator

Mountain Manor Treatment Center
Johns Hopkins University
3800 Frederick Ave.
Baltimore, MD 21229
gsubram@jhmi.edu

 

This ancillary study is related to CTN-0010, "Buprenorphine/Naloxone-Facilitated Rehabilitation for Heroin Addicted Adolescents/Young Adults."

The purpose of this study is to determine if adolescents with opioid use disorders (OUDs) have a greater number comorbidities than adolescents with marijuana and/or alcohol use disorders for substance use disorder diagnoses, psychiatric diagnoses, HIV-risk behaviors, and illegal acts. Ninety-four adolescents (ages 14-18 years) with a current OUD and 74 adolescents with a current non-OUD cannabis/alcohol use disorder were recruited from admissions, predominantly residential, to Mountain Manor, a substance abuse treatment program in Baltimore, Maryland. Participants were assessed cross-sectionally using standardized interviews and self-reports to determine group differences on demographic, substance use, psychiatric, and HIV-risk behaviors.

Primary Findings: The study confirmed that OUD adolescents evidenced greater impairment in academics, more substance use, more depressive symptoms, and higher IDU-related HIV-risk.

Primary Outcomes Paper: Subramaniam G, et al. Clinical characteristics of treatment-seeking adolescents with opioid versus cannabis/alcohol use disorders. Drug and Alcohol Dependence 2009;99:141-149. [more. . .]

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Supported by a grant from the National Institute on Drug Abuse to the University of Washington Alcohol and Drug Abuse Institute.
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