Stimulant Abuser Groups to Engage in 12-Step (STAGE-12): Evaluation of a Combined Individual-Group Intervention to Reduce Stimulant and Other Drug Use by Increasing 12-Step Involvement

Dennis M. Donovan, PhD
Co-Lead Investigator
Director, Alcohol and Drug Abuse Institute
University of Washington

Dennis Daley, PhD
Co-Lead Investigator
Chief, Addiction Medicine Services
Western Psychiatric Institute and Clinic

The primary objective of this protocol is to evaluate the degree to which a combined group and individual 12-Step facilitative intervention, Stimulant Abuser Groups to Engage in 12 -Step (STAGE-12), improves substance -related outcomes compared to treatment as usual (TAU) without STAGE-12 among stimulant abusers.  For this protocol, STAGE-12 will be integrated into treatment as usual.  The primary objective is to evaluate reduction in percent of days of stimulant use as measured by self-report.  This is a randomized, 2-group design comparing STAGE-12 integrated into TAU (STAGE-12 /TAU) to TAU without STAGE-12 for stimulant abusers receiving formal substance abuse treatment in participating community-based treatment programs (CTP).  A total of approximately 450 stimulant users seeking formal treatment, recruited from 10 CTPS, will be randomized.
CTN-0031 Study Protocol


Findings were mixed with respect to the impact of integrating the STAGE-12 intervention into intensive outpatient drug treatment compared with treatment as usual on stimulant drug use. However, the results more clearly indicate that individuals in STAGE-12 had higher rates of 12-step meeting attendance and were engaged in more related activities throughout both the active treatment phase and the entire 6-month follow-up period than did those in treatment as usual.

Primary Outcomes Article: Donovan DM, et al. Stimulant Abuser Groups to Engage in 12-Step (STAGE-12): A Multisite Trial in the National Institute on Drug Abuse Clinical Trials Network. Journal of Substance Abuse Treatment 2012;44(1):103-114. [get article]



Publications about CTN-0031

Study data from NIDA Data Share

Study Manual: Baker S, et al. STAGE-12: Stimulant Abuser Groups to Engage in 12-Step Programs: A Combined Group and Individual Treatment Program, v.3.0. Manual developed for National Drug Abuse Treatment Clinical Trials Network protocol CTN-0031, April 2009, 139 p. (NCT00573183)

NIDA protocol page

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Supported by a grant from the National Institute on Drug Abuse to the University of Washington Alcohol and Drug Abuse Institute.
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Updated 6/2012 --