PROTOCOL NIDA-CTN-0031-A-2


The Role of Alcohol Consumption in Classifications of Alcohol Use Disorders: A Clinical Study

Deborah Hasin, Ph.D.
Co-Lead Investigator
Columbia University and
New York State Psychiatric Institute
dsh2@columbia.edu

Dennis Donovan, Ph.D.
Co-Lead Investigator

Alcohol and Drug Abuse Institute
University of Washington
ddonovan@u.washington.edu

This CTN- and NIAAA-funded ancillary study is related to CTN-0031, "Stimulant Abusers Group to Engage in 12-Step (STAGE-12)."

This study will investigate the utility of adding a frequency measure of alcohol consumption to the DSM-V diagnostic criteria for alcohol use disorders, by analyzing the statistical performance of the alcohol consumption measure in conjunction with the other DSM-IV alcohol abuse and dependence criteria arrayed along a continuum of severity in clinical samples.  The alcohol consumption measure will be the frequency of drinking 5+ drinks (men) or 4+ drinks (women) on an occasion.  To accomplish this goal, the study will collect baseline data in clinical samples on the 5+/4+ alcohol consumption measure and DSM-IV alcohol abuse and dependence criteria.  These data will be used in two stages of analysis.  First, it will conduct IRT analyses to determine whether the diagnostic criteria in conjunction with the 5+/4+ consumption measure form patterns similar to those found in the NESARC.  In particular, it will focus on the role of the 5+/4+ consumption pattern when included in models that also include the DSM-IV alcohol abuse and dependence criteria.  Second, it will determine whether the alcohol severity indicator derived from the first stage of analysis predicts repeated measures of alcohol consumption collected at the follow-up points in the study.

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Supported by a grant from the National Institute on Drug Abuse to the University of Washington Alcohol and Drug Abuse Institute.
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Updated 2/2011 -- http://ctndisseminationlibrary.org/protocols/ctn0031a2.htm
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